Compromising emissions from a high speed cryptographic embedded system

Specific hardware implementations of cryptographic algorithms have been subject to a number of “side channel” attacks of late. A side channel is any information bearing emission that results from the physical implementation of a cryptographic algorithm. Smartcard realisations have been shown to be particularly vulnerable to these attacks. Other more complex embedded cryptographic systems may also be vulnerable, and each new design needs to be tested. The vulnerability of a recently developed high speed cryptographic accelerator is examined. The purpose of this examination is not only to verify the integrity of the device, but also to allow its designers to make a determination of its level of conformance with any standard that they may wish to comply with. A number of attacks were reviewed initially and two were chosen for examination and implementation - Power Analysis and Electromagnetic Analysis. These particular attacks appeared to offer the greatest threat to this particular system. Experimental techniques were devised to implement these attacks and a simulation and micrcontroller emulation were setup to ensure these techniques were sound. Each experimental setup was successful in attacking the simulated data and the micrcontroller circuit. The significance of this was twofold in that it verified the integrity of the setup and proved that a real threat existed. However, the attacks on the cryptographic accelerator failed in all cases to reveal any significant information. Although this is considered a positive result, it does not prove the integrity of the device as it may be possible for an adversary with more resources to successfully attack the board. It does however increase the level of confidence in this particular product and acts as a stepping stone towards conformance of cryptographic standards. The experimental procedures developed can also be used by designers wishing to test the vulnerability of their own products to these attacks

Practical packet combining for use with cooperative and non-cooperative ARQ schemes in wireless sensor networks

Although it is envisaged that advances in technology will follow a "Moores Law" trend for many years to come, one of the aims of Wireless Sensor Networks (WSNs) is to reduce the size of the nodes as much as possible. The issue of limited resources on current devices may therefore not improve much with future designs as a result. There is a pressing need, therefore, for simple, efficient protocols and algorithms that can maximise the use of available resources in an energy efficient manner. In this thesis an improved packet combining scheme useful on low power, resource-constrained sensor networks is developed. The algorithm is applicable in areas where currently only more complex combining approaches are used. These include cooperative communications and hybrid-ARQ schemes which have been shown to be of major benefit for wireless communications. Using the packet combining scheme developed in this thesis more than an 85% reduction in energy costs are possible over previous, similar approaches. Both simulated and practical experiments are developed in which the algorithm is shown to offer up to approximately 2.5 dB reduction in the required Signal-to-Noise ratio (SNR) for a particular Packet Error Rate (PER). This is a welcome result as complex schemes, such as maximal-ratio combining, are not implementable on many of the resource constrained devices under consideration. A motivational side study on the transitional region is also carried out in this thesis. This region has been shown to be somewhat of a problem for WSNs. It is characterised by variable packet reception rate caused by a combination of fading and manufacturing variances in the radio receivers. Experiments are carried out to determine whether or not a spread-spectrum architecture has any effect on the size of this region, as has been suggested in previous work. It is shown that, for the particular setup tested, the transitional region still has significant extent even when employing a spread-spectrum architecture. This result further motivates the need for the packet combining scheme developed as it is precisely in zones such as the transitional region that packet combining will be of most benefit

Wildlife Trade and Human Health in Lao PDR: An Assessment of the Zoonotic Disease Risk in Markets.

Although the majority of emerging infectious diseases can be linked to wildlife sources, most pathogen spillover events to people could likely be avoided if transmission was better understood and practices adjusted to mitigate risk. Wildlife trade can facilitate zoonotic disease transmission and represents a threat to human health and economies in Asia, highlighted by the 2003 SARS coronavirus outbreak, where a Chinese wildlife market facilitated pathogen transmission. Additionally, wildlife trade poses a serious threat to biodiversity. Therefore, the combined impacts of Asian wildlife trade, sometimes termed bush meat trade, on public health and biodiversity need assessing. From 2010 to 2013, observational data were collected in Lao PDR from markets selling wildlife, including information on volume, form, species and price of wildlife; market biosafety and visitor origin. The potential for traded wildlife to host zoonotic diseases that pose a serious threat to human health was then evaluated at seven markets identified as having high volumes of trade. At the seven markets, during 21 observational surveys, 1,937 alive or fresh dead mammals (approximately 1,009 kg) were observed for sale, including mammals from 12 taxonomic families previously documented to be capable of hosting 36 zoonotic pathogens. In these seven markets, the combination of high wildlife volumes, high risk taxa for zoonoses and poor biosafety increases the potential for pathogen presence and transmission. To examine the potential conservation impact of trade in markets, we assessed the status of 33,752 animals observed during 375 visits to 93 markets, under the Lao PDR Wildlife and Aquatic Law. We observed 6,452 animals listed by Lao PDR as near extinct or threatened with extinction. The combined risks of wildlife trade in Lao PDR to human health and biodiversity highlight the need for a multi-sector approach to effectively protect public health, economic interests and biodiversity

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field

A distributed protocol for object tracking in wireless multimedia sensor networks

We consider the problem of object tracking in a wireless multimedia sensor network (we mainly focus on the camera component in this work). The vast majority of current object tracking techniques, either centralised or distributed, assume unlimited energy, meaning these techniques don't translate well when applied within the constraints of low-power distributed systems. In this paper we develop and analyse a highly-scalable, distributed strategy to object tracking in wireless camera networks with limited resources. In the proposed system, cameras transmit descriptions of objects to a subset of neighbours, determined using a predictive forwarding strategy. The received descriptions are then matched at the next camera on the objects path using a probability maximisation process with locally generated descriptions. We show, via simulation, that our predictive forwarding and probabilistic matching strategy can significantly reduce the number of object-misses, ID-switches and ID-losses; it can also reduce the number of required transmissions over a simple broadcast scenario by up to 67%. We show that our system performs well under realistic assumptions about matching objects appearance using colour

Graphex 2 : 2nd Annual Juried Exhibition of Graphics with Purchase Awards

Director Belshaw describes the activities and organization of Graphex. Documentation of the selected works

Camera calibration in wireless multimedia sensor networks

Wireless Multi-media Sensor Networks (WMSNs) have become increasingly popular in recent years, driven in part by the increasing commoditization of small, low-cost CMOS sensors. As such, the challenge of automatically calibrating these types of cameras nodes has become an important research problem, especially for the case when a large quantity of these type of devices are deployed. This paper presents a method for automatically calibrating a wireless camera node with the ability to rotate around one axis. The method involves capturing images as the camera is rotated and computing the homographies between the images. The camera parameters, including focal length, principal point and the angle and axis of rotation can then recovered from two or more homographies. The homography computation algorithm is designed to deal with the limited resources of the wireless sensor and to minimize energy con- sumption. In this paper, a modified RANdom SAmple Consensus (RANSAC) algorithm is proposed to effectively increase the efficiency and reliability of the calibration procedure

What are the key conditions associated with lower limb amputations in a major Australian teaching hospital?

Background: Lower extremity amputation results in significant global morbidity and mortality. Australia appears to have a paucity of studies investigating lower extremity amputation. The primary aim of this retrospective study was to investigate key conditions associated with lower extremity amputations in an Australian population. Secondary objectives were to determine the influence of age and sex on lower extremity amputations, and the reliability of hospital coded amputations

Towards a framework for a versatile wireless multimedia sensor network platform

We describe our current work towards a framework that establishes a hierarchy of devices (sensors and actuators) within a wireless multimedia node and uses frequent sampling of cheaper devices to trigger the activation of more energy-hungry devices. Within this framework, we consider the suitability of servos for Wireless Multimedia Sensor Networks (WMSNs) by examining their functional characteristics and energy consumption [2]